Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Methylsulfonylmethane (MSM) is an organosulfur compound commonly used as a dietary supplement for its purported anti-inflammatory and pain-relieving properties. Its use for supporting or treating injuries, particularly musculoskeletal injuries, is primarily grounded in scientific research, though the quality and quantity of the evidence are limited. Several randomized controlled trials and animal studies have explored its potential benefits on inflammation, oxidative stress, and pain relief—factors relevant to injury recovery.

Some clinical studies indicate that MSM supplementation may reduce muscle soreness and joint pain following exercise-induced muscle damage, suggesting a possible role in supporting recovery from minor injuries. For instance, a 2012 study published in the Journal of Sports Medicine and Physical Fitness reported reduced muscle soreness after strenuous exercise among participants taking MSM. The proposed mechanisms include MSM’s antioxidant properties and its ability to modulate inflammatory cytokines.

However, the evidence base is still small, with mixed results and methodological limitations in many studies. There is inadequate high-quality clinical data directly supporting MSM’s use for treating acute injuries (e.g., sprains, fractures), and most research focuses on exercise recovery or chronic joint conditions like osteoarthritis. As such, while there is some scientific rationale for MSM’s use in supporting injury recovery, the overall evidence is modest, and more research is needed to establish its efficacy and optimal usage.

More about MSM (Methylsulfonylmethane)
More about Injuries

Other ingredients used for Injuries

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amino acids
bamboo
bayberry
beeswax
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bovine
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chymotrypsin
collagen
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Other health conditions supported by MSM (Methylsulfonylmethane)

Arthritis
Cartilage Damage
Fibromyalgia Syndrome
Inflammation
Injuries
Pain (general remedies for)
Sprains

Products containing MSM (Methylsulfonylmethane)

We currently have no products on Vitabase that contain this ingredient.