Evidence supporting the use of: P-menthane-3,8-diol
For the health condition: Insect Repellant

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

P-menthane-3,8-diol (PMD) is a naturally derived compound primarily obtained from the distillation of the oil of lemon eucalyptus (Corymbia citriodora). Its use as an insect repellent is supported by robust scientific evidence. PMD has been extensively studied and is recognized by leading health authorities, including the U.S. Centers for Disease Control and Prevention (CDC) and the Environmental Protection Agency (EPA), as an effective active ingredient in insect repellents. Multiple controlled studies have demonstrated that PMD provides protection against mosquitoes, including those capable of transmitting diseases such as malaria and West Nile virus. In head-to-head comparisons, PMD-based repellents (at appropriate concentrations) have shown efficacy comparable to DEET, the gold standard for insect repellency, often providing several hours of protection.

The mechanism of action involves disrupting the mosquito’s ability to detect human hosts by interfering with olfactory receptors. PMD’s effectiveness has led to its inclusion in commercial repellent products, particularly for those seeking botanical alternatives to synthetic chemicals. Safety data indicate low toxicity and minimal skin irritation when used as directed, and PMD is approved for use on children over three years old. The scientific consensus strongly supports PMD’s role as an effective and reliable insect repellent, and its use is grounded in peer-reviewed research, regulatory acceptance, and real-world application.

More about p-menthane-3,8-diol
More about Insect Repellant

Other health conditions supported by p-menthane-3,8-diol

Bites and Stings
Insect Repellant

Products containing p-menthane-3,8-diol

We currently have no products on Vitabase that contain this ingredient.