Evidence supporting the use of: Bacopasaponin (unspecified)
For the health condition: Insomnia
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Bacopasaponins are the active saponin constituents of Bacopa monnieri, a herb traditionally used in Ayurvedic medicine. Bacopa monnieri is primarily known for its cognitive-enhancing and anxiolytic effects, but it has also been used in traditional systems to promote relaxation and improve sleep. Historical Ayurvedic texts describe Bacopa (Brahmi) as a "Medhya Rasayana" (nootropic and nervine tonic), and practitioners have used it for insomnia, although this is less emphasized compared to its memory-boosting properties. The evidence supporting its use for insomnia is largely based on traditional use and anecdotal reports.
Scientific studies on Bacopa monnieri have focused mainly on cognition, anxiety, and neuroprotection. A few animal studies suggest that Bacopa extracts can have sedative and anxiolytic effects, potentially via modulation of neurotransmitters such as serotonin and GABA. However, well-designed human clinical trials specifically investigating Bacopasaponins or Bacopa extracts for insomnia or sleep disorders are lacking. Some studies that measured secondary sleep outcomes in trials primarily assessing anxiety or cognition have hinted at improved sleep quality, but these findings are not robust or conclusive. Thus, while traditional use exists and there are plausible mechanisms, scientific validation for Bacopasaponins as a treatment for insomnia is limited.
Other ingredients used for Insomnia
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
benegut perilla (proprietary)
black cumin
Indian frankincense
rice
calcium
California poppy
cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
greek mountain tea
heartwood
hops
jujube
kava root
kudzu
l-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
tangerine
anise
blackboard tree
lingzhi
lingusticum wallichii
morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
wood betony
goji berry
soursop
Aralia
Agastache
Alpha-terpineol
Angelica
Apigenin
Anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
Atractylone
Betony
Black Seed
Baikal Skullcap
Blackthorn
Balsam
Bayleaf
Big Quaking Grass
Banyan
Brahmi
Borassus Palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
Carry Me Seed
Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
Carthamus
Clerodendrum indicum
Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Glycine
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
Orchid
Poppy
Rose
Spikenard
Sandalwood
Sumac
Sweet Orange alcohol
Vervain
walnut
Other health conditions supported by Bacopasaponin (unspecified)
Alzheimer's DiseaseAnxiety
Anxiety Disorders
Asthma
Cough (general)
Digestion (poor)
Fatigue
Gastritis
Headache (general)
Inflammation
Insomnia
Memory and Brain Function
Stress
Ulcers
Wounds and Sores