Evidence supporting the use of: California poppy
For the health condition: Insomnia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

California poppy (Eschscholzia californica) has a long tradition of use in herbal medicine, particularly among Native American populations and later in European herbal traditions, as a mild sedative and sleep aid. In modern times, its use for supporting or treating insomnia has been investigated in several preclinical and some small clinical studies. The plant contains several alkaloids, such as protopine and allocryptopine, which are believed to interact with the central nervous system, possibly by modulating GABAergic activity, leading to mild sedative and anxiolytic effects.

A few clinical trials have evaluated preparations containing California poppy, often in combination with other herbs like valerian. These studies suggest some mild improvement in sleep quality and latency compared to placebo, but they are generally small, short-term, and sometimes lack rigorous controls. For example, a 2019 randomized placebo-controlled trial found a combination of California poppy and valerian improved sleep onset and quality in people with mild insomnia. However, there are very few studies on California poppy as a standalone treatment, and systematic reviews typically conclude that while the herb appears safe and shows promise, the evidence is still insufficient for strong recommendations.

Overall, the use of California poppy for insomnia is justified by a combination of traditional use and emerging, though limited, scientific evidence. More high-quality, large-scale clinical trials are needed to confirm its efficacy and define its role in treating insomnia.

More about California poppy
More about Insomnia

Other ingredients used for Insomnia

5-Hydroxytryptophan (5-HTP)
amino acids
ashwagandha
waterhyssop
benegut perilla (proprietary)
black cumin
Indian frankincense
rice
calcium
California poppy
cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
greek mountain tea
heartwood
hops
jujube
kava root
kudzu
l-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
tangerine
anise
blackboard tree
lingzhi
lingusticum wallichii
morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
wood betony
goji berry
soursop
Aralia
Agastache
Alpha-terpineol
Angelica
Apigenin
Anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
Atractylone
Betony
Black Seed
Baikal Skullcap
Blackthorn
Balsam
Bayleaf
Big Quaking Grass
Banyan
Brahmi
Borassus Palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
Carry Me Seed
Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
Carthamus
Clerodendrum indicum
Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Glycine
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
Orchid
Poppy
Rose
Spikenard
Sandalwood
Sumac
Sweet Orange alcohol
Vervain
walnut

Other health conditions supported by California poppy

Anxiety
Insomnia
Pain (general remedies for)
Stress
Tension