Evidence supporting the use of: Cannabidiol
For the health condition: Insomnia
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cannabidiol (CBD) is increasingly used as a supplement to support sleep and treat insomnia. Scientific interest in CBD for sleep arises from its interaction with the endocannabinoid system, which is involved in regulating sleep-wake cycles. Small clinical studies and anecdotal reports suggest that CBD may help improve sleep quality, reduce sleep disturbances, and decrease the time it takes to fall asleep for some individuals. For instance, a 2019 clinical trial published in The Permanente Journal found that CBD improved sleep in about two-thirds of participants over a one-month period; however, the sample size was small and the study was open-label, limiting the strength of the evidence.
Experimental research suggests that CBD may reduce anxiety, which is often a contributing factor to insomnia. By potentially lowering anxiety levels, CBD may indirectly aid in falling and staying asleep. However, larger randomized controlled trials are needed to confirm these effects. The available evidence is mixed, with some studies showing benefit and others showing no significant effect. Currently, the use of CBD for insomnia is considered supported by preliminary scientific evidence but not yet validated by large-scale, rigorous clinical trials. Therefore, the evidence rating for CBD’s use in insomnia is modest (2 out of 5).
Other ingredients used for Insomnia
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
Waterhyssop
benegut perilla (proprietary)
black cumin
Indian frankincense
rice
calcium
California poppy
cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
Greek mountain tea
heartwood
hops
jujube
kava
kudzu
L-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
Marine lipid
Melatonin
Moringa
Motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
Valerian root
vitamin B6
Zinc
catnip
tangerine
anise
blackboard tree
lingzhi
Szechuan lovage
Morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
Wood betony
goji berry
soursop
Aralia
Agastache
alpha-terpineol
Angelica
apigenin
anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
atractylone
betony
black seed
Baikal Skullcap
blackthorn
balsam
bayleaf
big quaking grass
banyan
brahmi
borassus palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese silkvine
Clary sage
Clerodendrum trichotomum
cactus
Cyathula
citron
carry me seed
cannabinol
Cymbopogon martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
corktree
cowslip
cannabidiol
calamus
cherimoya
Corydalis
Carthamus
Clerodendrum indicum
dragonhead
David\'s milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
elk antler
elephant\'s head
Embelia
Flueggea suffruticosa
Ficus religiosa
Ficus simplicissima
fringed pink
frankincense
Gelsemium
geraniol
giant blazingstar
Glycine
Gardenia jasminoides
Homalomena
honeybush
jasmine
Jatoba
jujubosides
Jatamansi
kavalactones
Kukicha
kiwi
Lycium
loquat
lemon balm
Lactucarium
Lady of the Night
Lesser speargrass
Lilium polyphyllum
linden
longan
Lindera
lotus
labrador tea
Large-leaved linden
lily
little ironweed
lupulinum
Loranthus
linalool
Mesua
Myrcene
Marjoram
mallow
mace
Milk Protein
Matapalo Tree
Mimosa
Microtea debilis
Morning glory
magnolol
Mulungu
Macaranga indica
Nardostachys
Night jessamine
Nymphaea caerulea
Nymphaea nouchali
Ophiopogon
Oroxylum indicum
Onosma bracteatum
orchid
Osmanthus
Osthole
Premna
polysaccharides
Pulsatilla
Patchouli oil
phlorotannins
Portulaca
Passionfruit
Polygonatum
Pimpinella
Persimmon
paeoniflorin
poppy
Polygonum
Polygala
rue
Rauvolfia
Rubiaceae
rose
Rooibos
Speedwell
Scoparia dulcis
Sumbul
Self-Heal
Sweet Annie
Spikenard
Salvia
Sensitive Plant
Southernwood
Sarivan
Shankhpushpi
Sweet Woodruff
Schisandrins
Sandalwood
Semecarpus anacardium
Stachytarpheta cayennensis
Sumac
Sweet Bay
Sword Bean
Safranal
Sedanenolide
Sweet Orange alcohol
Terminalia
Tagara
Tetrahydropalmatine
Vetiver
Valerenic acid
Vervain
Verbena
Withanolides
Wax Gourd
Walnut
Winter Begonia
Winter Savory
Yuzu
Yellow-Fruit Nightshade
Ylang ylang
Other health conditions supported by cannabidiol
AnxietyAnxiety Disorders
Arthritis
Autism
Backache
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Convulsions
Crohn's Disease
Depression
Dermatitis
Epilepsy
Fibromyalgia Syndrome
Headache (general)
Inflammation
Inflammatory Bowel Disorders
Insomnia
Irritable Bowel Syndrome
Migraine
Multiple Sclerosis
Nausea and Vomiting
Nerve Damage
Nervousness
Neuralgia and Neuritis
Obsessive Compulsive Disorder
Pain (general remedies for)
Parkinson's Disease
Post Traumatic Stress Disorder
Psoriasis
Rheumatoid Arthritis