Evidence supporting the use of: Osthole
For the health condition: Insomnia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Osthole is a natural coumarin compound found in several medicinal plants, most notably Cnidium monnieri. Its use in supporting or treating insomnia is primarily rooted in traditional medicine, especially within Chinese herbal practices. In Traditional Chinese Medicine (TCM), Cnidium monnieri has been used for various purposes, including as a tonic for reproductive health, but reports of its direct use for insomnia are limited and typically anecdotal. While some animal studies have indicated that osthole may possess central nervous system activities, such as anti-anxiety or neuroprotective effects, there is currently minimal direct scientific evidence supporting its efficacy for insomnia specifically. The few experimental studies that exist are preliminary, often conducted in vitro or in animal models, and do not establish a clear mechanism or clinical benefit for sleep disorders. Human clinical trials are lacking. Therefore, while osthole is sometimes included in traditional formulations for calming effects, its use for insomnia is not well-supported by either robust traditional documentation or scientific validation. Overall, the evidence base is weak, and further research is needed to clarify any potential benefit for this condition.

More about Osthole
More about Insomnia

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amino acids
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calcium
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cassia bark
chamomile
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cinnamon
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fennel
GABA (gamma aminobutyric acid)
gooseberry
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kava root
kudzu
l-tryptophan
lactium casein decapeptide
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maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
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anise
blackboard tree
lingzhi
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morus
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chrysanthemum
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ganoderma
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aster root
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wood betony
goji berry
soursop
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Alpha lactalbumin
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Atractylone
Betony
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Blackthorn
Balsam
Bayleaf
Big Quaking Grass
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Borassus Palm
Borassus aethiopum
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Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
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Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
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Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Glycine
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
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Poppy
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walnut

Products containing Osthole

We currently have no products on Vitabase that contain this ingredient.