Evidence supporting the use of: Polygonatum
For the health condition: Insomnia
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Polygonatum, commonly known as Solomon's Seal, has a long history of use in traditional Chinese medicine (TCM) and other Asian herbal systems. In TCM, the rhizome of Polygonatum species (especially Polygonatum sibiricum and Polygonatum odoratum) is used to nourish yin, moisten dryness, and tonify the lungs and kidneys. It is sometimes included in herbal formulas intended to address symptoms related to insomnia, such as restlessness, night sweats, or general weakness, based on the belief that strengthening yin and calming internal imbalances can help promote restful sleep.
Despite this traditional use, scientific validation for Polygonatum's efficacy in treating insomnia is limited. Most available studies focus on its antioxidant, anti-inflammatory, and immunomodulatory effects, rather than direct effects on sleep quality or insomnia. A few animal studies suggest potential sedative or anxiolytic effects, but these are preliminary and do not provide robust evidence for clinical effects in humans. Systematic reviews and clinical trials specifically focused on insomnia are lacking as of 2024. Therefore, while Polygonatum is traditionally used for symptoms that might co-occur with insomnia, its direct effectiveness for sleep disorders remains unproven from a scientific standpoint.
In summary, the use of Polygonatum for insomnia is primarily justified by traditional medicine practices, with modest historical evidence and very limited scientific support.
Other ingredients used for Insomnia
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
benegut perilla (proprietary)
black cumin
Indian frankincense
rice
calcium
California poppy
cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
greek mountain tea
heartwood
hops
jujube
kava root
kudzu
l-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
tangerine
anise
blackboard tree
lingzhi
lingusticum wallichii
morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
wood betony
goji berry
soursop
Aralia
Agastache
Alpha-terpineol
Angelica
Apigenin
Anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
Atractylone
Betony
Black Seed
Baikal Skullcap
Blackthorn
Balsam
Bayleaf
Big Quaking Grass
Banyan
Brahmi
Borassus Palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
Carry Me Seed
Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
Carthamus
Clerodendrum indicum
Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Glycine
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
Orchid
Poppy
Rose
Spikenard
Sandalwood
Sumac
Sweet Orange alcohol
Vervain
walnut
Other health conditions supported by Polygonatum
Abdominal PainAnemia
Appetite (deficient)
Asthma
Backache
Bronchitis
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Chills
Cholesterol (high)
Colds (general)
Constipation (adults)
Cough (general)
Cramps and Spasms
Depression
Diabetes
Diarrhea
Digestion (poor)
Dizziness
Edema
Energy (lack of)
Fatigue
Fever
Gastritis
Glands (swollen lymph)
Heart (weakness)
Hypertension
Indigestion
Inflammation
Influenza
Insomnia
Jaundice (adults)
Liver Detoxification
Nausea and Vomiting
Nephritis