Polygonatum cirrhifolium, commonly known as "Himalayan Solomon's Seal," has a long-standing use in traditional medicine systems such as Ayurveda and folk medicine in the Himalayan region. Its rhizomes are used to prepare herbal remedies for a variety of ailments, including as a general tonic and for relief of stress-related symptoms. In the context of insomnia, traditional practitioners sometimes recommend Polygonatum species for their purported calming and adaptogenic effects. However, specific documentation of P. cirrhifolium being widely or consistently used for insomnia, as opposed to general nervous disorders, is limited in historical texts. The broader genus Polygonatum has been cited in some ethnobotanical surveys as a traditional remedy for sleep disturbances or anxiety.

Despite these traditional uses, there is a lack of robust scientific studies investigating Polygonatum cirrhifolium or its phytochemical constituents for sedative, anxiolytic, or hypnotic effects directly relevant to insomnia. Most available research focuses on its antioxidant, anti-inflammatory, or adaptogenic properties. Therefore, the justification for its use in insomnia is primarily traditional, and the level of evidence supporting this use is weak (rated 1 out of 5), mainly based on ethnobotanical reports and historical usage rather than clinical or pharmacological validation.