Evidence supporting the use of: Rubiaceae (unspecified)
For the health condition: Insomnia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of Rubiaceae plants for the treatment of insomnia is primarily based on traditional medicine rather than robust scientific validation. Various species within the Rubiaceae family, such as Gardenia jasminoides and Coffea species, have a long history of ethnobotanical use in different cultures, particularly in Asia and Africa, where preparations from these plants have been used as mild sedatives or sleep aids. For example, Gardenia jasminoides (fruit) has been utilized in traditional Chinese medicine for its purported calming effects, often in combination with other herbs to address restlessness or disturbed sleep. However, the active compounds responsible for these effects are not well-characterized, and modern pharmacological studies are limited.

Scientific research into the sedative or hypnotic properties of Rubiaceae members is sparse and often inconclusive. Some preclinical studies suggest possible central nervous system depressant activity in certain extracts, but these findings are preliminary and not sufficient to establish efficacy or safety for insomnia treatment. In contrast, other notable Rubiaceae plants like coffee (Coffea spp.) contain caffeine and are more likely to cause insomnia rather than treat it. Overall, while traditional use is documented, high-quality clinical evidence is lacking, and the evidence supporting the use of unspecified Rubiaceae for insomnia rates low (2/5).

More about Rubiaceae (unspecified)
More about Insomnia

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amino acids
ashwagandha
waterhyssop
benegut perilla (proprietary)
black cumin
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rice
calcium
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cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
greek mountain tea
heartwood
hops
jujube
kava root
kudzu
l-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
tangerine
anise
blackboard tree
lingzhi
lingusticum wallichii
morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
wood betony
goji berry
soursop
Aralia
Agastache
Alpha-terpineol
Angelica
Apigenin
Anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
Atractylone
Betony
Black Seed
Baikal Skullcap
Blackthorn
Balsam
Bayleaf
Big Quaking Grass
Banyan
Brahmi
Borassus Palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
Carry Me Seed
Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
Carthamus
Clerodendrum indicum
Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Glycine
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
Orchid
Poppy
Rose
Spikenard
Sandalwood
Sumac
Sweet Orange alcohol
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walnut

Products containing Rubiaceae (unspecified)

We currently have no products on Vitabase that contain this ingredient.