Sweet Annie (Artemisia annua), also known as Qinghao, has a long history of use in traditional Chinese medicine, primarily for treating fevers and malaria. Its use for insomnia, however, is far less prominent and is generally based on folk or anecdotal traditions rather than mainstream herbal practice. Some traditional herbalists have included Sweet Annie in formulas believed to have a calming effect, but this is not a widespread or well-established use in major historical texts. In traditional Chinese medicine, insomnia is usually treated with other herbs, and Sweet Annie is rarely highlighted for this purpose.

Scientifically, research on Sweet Annie has focused almost exclusively on its antimalarial properties (due to its active compound artemisinin) and its potential antiviral and anti-inflammatory effects. There are no robust clinical studies, animal models, or pharmacological investigations supporting its efficacy for insomnia or sleep disorders. The evidence that does exist is limited to occasional references in herbal compendia or anecdotal reports, and there is no mechanistic explanation or clinical validation for its use in sleep support. Therefore, the use of Sweet Annie for insomnia is justified primarily by minor traditional claims, and the evidence supporting this application is very weak.