Evidence supporting the use of: Tetrahydrocannabinol
For the health condition: Insomnia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Tetrahydrocannabinol (THC), the primary psychoactive compound found in cannabis, has been studied for its potential effects on sleep and insomnia. Historically, cannabis has been used for sleep disturbances in various cultures, but modern use of isolated THC is supported by a small but growing body of scientific literature. Clinical studies suggest that THC can reduce sleep latency (the time it takes to fall asleep) and may increase overall sleep duration. For example, a 2017 systematic review published in Current Psychiatry Reports notes that some studies demonstrate improved sleep outcomes with THC or cannabis use, particularly among individuals with chronic pain or other medical conditions. However, the evidence is mixed: some studies report impaired sleep quality, tolerance with chronic use, and possible withdrawal-related sleep disturbances. Additionally, THC may alter the proportions of sleep stages, such as reducing REM sleep, which could have negative effects on sleep quality over time.

Most expert guidelines do not recommend THC as a first-line treatment for insomnia due to the limited quality and quantity of available evidence, potential for dependence, and side effects such as cognitive impairment or next-day drowsiness. In summary, while there is some scientific validation for THC's sleep-inducing properties, the overall strength of evidence for its use in treating insomnia is low to moderate, and concerns remain about long-term safety and efficacy.

More about Tetrahydrocannabinol
More about Insomnia

Other ingredients used for Insomnia

5-Hydroxytryptophan (5-HTP)
amino acids
ashwagandha
waterhyssop
benegut perilla (proprietary)
black cumin
Indian frankincense
rice
calcium
California poppy
cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
greek mountain tea
heartwood
hops
jujube
kava root
kudzu
l-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
tangerine
anise
blackboard tree
lingzhi
lingusticum wallichii
morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
wood betony
goji berry
soursop
Aralia
Agastache
Alpha-terpineol
Angelica
Apigenin
Anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
Atractylone
Betony
Black Seed
Baikal Skullcap
Blackthorn
Balsam
Bayleaf
Big Quaking Grass
Banyan
Brahmi
Borassus Palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
Carry Me Seed
Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
Carthamus
Clerodendrum indicum
Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Glycine
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
Orchid
Poppy
Rose
Spikenard
Sandalwood
Sumac
Sweet Orange alcohol
Vervain
walnut

Products containing Tetrahydrocannabinol

We currently have no products on Vitabase that contain this ingredient.