Evidence supporting the use of: Albizia julibrissin
For the health condition: Irritability

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Albizia julibrissin, commonly known as the Persian silk tree or mimosa, has a long history of traditional use in Chinese medicine, where it is known as "He Huan Pi" (the bark) or "He Huan Hua" (the flower). In Traditional Chinese Medicine (TCM), Albizia is used to "calm the spirit," relieve irritability, alleviate anxiety, and treat insomnia. Historical texts, such as the "Shennong Bencao Jing," describe its use for calming emotions and supporting mood balance. The traditional rationale is based on the belief that Albizia nourishes the heart and calms the mind.

Regarding scientific evidence, some preliminary animal studies and in vitro research suggest that extracts of Albizia julibrissin may have anxiolytic (anxiety-reducing) and antidepressant-like effects, possibly through modulation of neurotransmitters such as serotonin. However, robust clinical trials in humans are lacking, and the available scientific evidence is insufficient to conclusively validate its efficacy for irritability or related mood disturbances. The evidence rating of 2 reflects the existence of suggestive preclinical studies and strong traditional use, but a lack of high-quality human research.

In summary, Albizia julibrissin is primarily used for irritability based on traditional practices, with only limited and preliminary scientific support. More rigorous research is needed to confirm its effects and safety for this indication.

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