Evidence supporting the use of: Belladonna
For the health condition: Irritability

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Belladonna (Atropa belladonna), also known as deadly nightshade, has been used traditionally in herbal medicine for a variety of conditions, including irritability. Its use in this context is primarily linked to historical and homeopathic practices rather than modern scientific validation. In homeopathy, belladonna is often recommended for acute states of agitation, restlessness, or irritability, especially when these symptoms are accompanied by redness, heat, and sudden onset, based on the principle of "like cures like." Additionally, in traditional Western herbal medicine, belladonna was used as a sedative and antispasmodic, believed to calm the nervous system. However, there is minimal scientific evidence to support the efficacy or safety of belladonna for treating irritability. The plant contains tropane alkaloids such as atropine, scopolamine, and hyoscyamine, which exert anticholinergic effects and can cause delirium, confusion, and agitation at toxic doses, potentially worsening irritability rather than alleviating it. The risks associated with belladonna toxicity are significant, and its medicinal use is largely obsolete in mainstream medicine. Modern clinical studies evaluating belladonna specifically for irritability are lacking. In summary, belladonna's use for irritability is rooted in traditional and homeopathic frameworks, but it lacks robust scientific validation, and safety concerns further limit its application.

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