Evidence supporting the use of: Reishi mushroom
For the health condition: Irritability

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has a long history of use in Traditional Chinese Medicine (TCM), where it is known as "Lingzhi." Traditionally, reishi is considered a "shen tonic," meaning it is used to calm the spirit, nourish the heart, and support emotional balance. In TCM, irritability is often associated with imbalances involving the heart, liver, or spleen, and reishi is sometimes prescribed as part of herbal formulas to help address symptoms such as restlessness, anxiety, and mild irritability. The rationale is rooted in reishi's reputed ability to "nourish the heart and tranquilize the mind."

From a scientific perspective, there is limited evidence directly supporting reishi's use specifically for irritability. Some preliminary studies and animal research suggest that reishi extracts may have adaptogenic and anti-stress effects, possibly by modulating neurotransmitter activity and reducing markers of stress. However, clinical studies in humans directly examining its effects on irritability are lacking. Most of the claims for its calming effects are extrapolated from traditional use and from studies on related symptoms such as anxiety or sleep disturbances.

In summary, reishi's use for irritability is primarily justified by tradition, with only weak indirect scientific support. Its role in calming the mind and reducing irritability remains largely anecdotal and based on historical use rather than robust clinical evidence.

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