Evidence supporting the use of: Bacillus coagulans
For the health condition: Irritable Bowel Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bacillus coagulans is a spore-forming probiotic bacterium that is increasingly studied for its potential benefits in gastrointestinal disorders, including Irritable Bowel Syndrome (IBS). Scientific evidence supporting its use is growing, though it is not yet at the highest level of clinical endorsement. Several randomized, double-blind, placebo-controlled trials have investigated B. coagulans in IBS patients. For example, a 2009 study published in Digestive Diseases and Sciences found that daily supplementation with B. coagulans GBI-30, 6086 significantly improved abdominal pain and bloating compared to placebo. Other studies have reported positive effects on stool frequency, consistency, and global IBS symptoms. The proposed mechanisms include modulation of the gut microbiota, enhancement of short-chain fatty acid production, and anti-inflammatory effects.

While the body of clinical evidence is growing, it is important to note that studies often vary in strain, dosage, and patient population. Most registered benefits pertain to improvements in overall symptom scores and quality of life, rather than complete resolution of IBS. Major gastroenterological societies have not yet universally endorsed B. coagulans as a primary IBS treatment, but some guidelines recognize it as a potentially useful adjunct. In summary, there is moderate, but not conclusive, scientific support for the use of B. coagulans in IBS, earning it a rating of 3 out of 5 for evidence strength.

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