Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Butyrate triglyceride is used as a means of delivering butyrate, a short-chain fatty acid (SCFA), to the colon. There is a growing body of scientific evidence suggesting that butyrate plays a key role in maintaining gut health and modulating inflammation, both of which are important in the management of Irritable Bowel Syndrome (IBS). Butyrate is a major energy source for colonocytes and has been shown in vitro and in animal studies to enhance intestinal barrier function, reduce visceral hypersensitivity, and exert anti-inflammatory effects. Clinical studies have demonstrated that oral butyrate supplementation, often in the form of microencapsulated sodium butyrate or butyrate triglycerides, can reduce IBS symptoms, particularly abdominal pain and bloating. For example, randomized controlled trials (RCTs) published in peer-reviewed journals have reported statistically significant improvements in IBS symptoms with butyrate supplementation compared to placebo. However, while the data is promising, the number of high-quality, large-scale clinical trials is still relatively limited, and further research is needed to establish optimal dosing, long-term safety, and efficacy across all IBS subtypes. Overall, the use of butyrate triglyceride for IBS is grounded in scientific study rather than tradition, with moderate evidence supporting its benefit.

More about butyrate triglyceride
More about Irritable Bowel Syndrome

Other ingredients used for Irritable Bowel Syndrome

Other health conditions supported by butyrate triglyceride

Products containing butyrate triglyceride

Douglas Laboratories MCT/Butyrate Liquid with SunButyrate™
Pure Encapsulations SunButyrate-TG