Evidence supporting the use of: Cannabidiol
For the health condition: Irritable Bowel Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabidiol (CBD) is a non-psychoactive compound derived from the cannabis plant. Its use for supporting or treating Irritable Bowel Syndrome (IBS) is based on growing scientific interest, though robust clinical validation is limited. Preclinical studies suggest CBD interacts with the endocannabinoid system, which plays a role in gastrointestinal motility, inflammation, and visceral pain—key factors in IBS pathology. Animal studies have demonstrated that cannabinoids can reduce gut inflammation and modulate motility, but these findings do not directly translate to CBD or to human IBS.

A handful of small-scale human studies and case reports have explored the effects of CBD and cannabis extracts in functional gut disorders, including IBS, but results are inconsistent. Some patients report symptom relief, particularly regarding abdominal pain and bloating, but controlled clinical trials are scarce. A 2020 review concluded that while there is a biological basis for considering cannabinoids in IBS, high-quality evidence for efficacy and safety is lacking.

In summary, scientific interest in CBD for IBS is driven largely by mechanistic plausibility and preclinical data, not by strong clinical evidence. More rigorous, controlled human trials are needed to establish its benefit and safety profile in IBS patients.

More about Cannabidiol
More about Irritable Bowel Syndrome

Other ingredients used for Irritable Bowel Syndrome

2'-Fucosyllactose
akkermansia muciniphila
aloe vera
alpha-galactosidase
alpha-pinene
amino acids
bacillus clausii
bacillus coagulans
bacillus subtilis
benegut perilla (proprietary)
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blackberry
Indian frankincense
butyrate triglyceride
chen pi
chia seed
chlorella
cinnamon
turmeric
curcumin
fennel
flaxseed
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
ginger
green banana
green tea
guar gum
cellulose
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lovage
marshmallow
oat
pectin
peppermint oil
plum fruit
pomegranate
potato starch
butyric acid
psyllium
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
spearmint leaf
streptococcus thermophilus
tributyrin
vitamin D
xylooligosaccharides
zinc
hyssop
atractylodes
ferula assafoetida
anise
holarrhena antidysenterica
fumaria parviflora
chrysanthemum
senna
white oak
algae
Agastache
Asafoetida
Alexandrian senna
Agrimonia pilosa
Betony
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Boswellic Acid
Bayleaf
Belleric myrobalan
Bran
Boswellia
Bacillus licheniformis
black salt
Bifidobacterium animalis
Bitter principals
Bacteria
Bifidobacteria
Bacillus
Cumin
Coriander
Citron
Cannabidiol
Clerodendrum indicum
Dragonhead
Dichrostachys glomerata
Enterococcus
Enzyme Blend
Fig
Fiber
Quince
Rhubarb

Products containing Cannabidiol

We currently have no products on Vitabase that contain this ingredient.