Evidence supporting the use of: Cannabis
For the health condition: Irritable Bowel Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cannabis and its derivatives have been explored for the management of symptoms associated with Irritable Bowel Syndrome (IBS), primarily due to their effects on the endocannabinoid system, which plays a role in gut motility, pain perception, and inflammation. Some patients with IBS report symptom relief with cannabis, and small studies have suggested that cannabinoids may reduce abdominal pain and improve general well-being in patients with gastrointestinal disorders. However, high-quality clinical evidence specifically addressing IBS is limited. Most available studies are small, open-label, or observational rather than randomized controlled trials. For example, a 2011 study found that dronabinol (a synthetic cannabinoid) affected colonic motility, but its clinical significance in IBS symptom management remains unclear. There is a plausible biological basis for efficacy due to the presence of cannabinoid receptors in the gastrointestinal tract, but the overall scientific support is considered modest (evidence rating: 2 out of 5). Current clinical guidelines do not recommend cannabis as a standard treatment for IBS, citing insufficient evidence of efficacy and concerns about side effects and long-term safety. More robust, large-scale randomized trials are needed to clarify the therapeutic potential and safety profile of cannabis in IBS management.
Other ingredients used for Irritable Bowel Syndrome
2'-Fucosyllactoseakkermansia muciniphila
aloe vera
alpha-galactosidase
alpha-pinene
amino acids
bacillus clausii
bacillus coagulans
bacillus subtilis
benegut perilla (proprietary)
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blackberry
Indian frankincense
butyrate triglyceride
chen pi
chia seed
chlorella
cinnamon
turmeric
curcumin
fennel
flaxseed
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
ginger
green banana
green tea
guar gum
cellulose
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lovage
marshmallow
oat
pectin
peppermint oil
plum fruit
pomegranate
potato starch
butyric acid
psyllium
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
spearmint leaf
streptococcus thermophilus
tributyrin
vitamin D
xylooligosaccharides
zinc
hyssop
atractylodes
ferula assafoetida
anise
holarrhena antidysenterica
fumaria parviflora
chrysanthemum
senna
white oak
algae
Agastache
Asafoetida
Alexandrian senna
Agrimonia pilosa
Betony
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Boswellic Acid
Bayleaf
Belleric myrobalan
Bran
Boswellia
Bacillus licheniformis
black salt
Bifidobacterium animalis
Bitter principals
Bacteria
Bifidobacteria
Bacillus
Cumin
Coriander
Citron
Cannabidiol
Clerodendrum indicum
Dragonhead
Dichrostachys glomerata
Enterococcus
Enzyme Blend
Fig
Fiber
Quince
Rhubarb
Other health conditions supported by Cannabis
Abdominal PainAcquired Immune Deficiency Syndrome
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Alcoholism
Alzheimer's Disease
Anxiety
Anxiety Disorders
Appetite (deficient)
Arthritis
Asthma
Backache
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Crohn's Disease
Depression
Dysmenorrhea
Epilepsy
Glaucoma
Headache (cluster)
Headache (general)
Headache (sinus)
Headache (tension)
Inflammation
Insomnia
Irritable Bowel Syndrome
Lupus