Evidence supporting the use of: Hyperimmune milk peptides
For the health condition: Irritable Bowel Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hyperimmune milk peptides are derived from cows immunized with specific antigens, resulting in milk rich in immunoglobulins and bioactive peptides. There is some emerging scientific evidence supporting their use in Irritable Bowel Syndrome (IBS), though the quality and quantity of data remain limited. A few small-scale randomized clinical trials and pilot studies have explored the effects of hyperimmune bovine colostrum or milk products on IBS symptoms. These studies suggest modest benefits in reducing symptoms such as bloating, abdominal pain, and stool irregularities, potentially by modulating gut immunity, reducing intestinal inflammation, and improving gut barrier function. However, most studies have small sample sizes, short durations, and sometimes lack rigorous controls. For example, a double-blind, placebo-controlled study published in Alimentary Pharmacology & Therapeutics (2002) observed some symptom improvement in IBS patients supplementing with immune milk, but the effect size was modest and not all symptom domains improved. The proposed mechanisms involve the neutralization of gut pathogens, modulation of mucosal immune responses, and restoration of gut barrier integrity, which are relevant to the pathophysiology of IBS. Despite these promising findings, meta-analyses and systematic reviews have concluded that the evidence remains preliminary. Larger, high-quality trials are needed to confirm efficacy and safety. Thus, while there is some scientific rationale and limited supportive data, the overall evidence base is weak to moderate at best.

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Products containing Hyperimmune milk peptides

We currently have no products on Vitabase that contain this ingredient.