Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Propionibacterium freudenreichii is a species of probiotic bacterium traditionally used in cheese fermentation (notably Swiss cheese), but it has recently gained attention for potential health benefits, including gut health support. Regarding Irritable Bowel Syndrome (IBS), the evidence supporting its use is preliminary but growing. A few pilot clinical trials and in vitro studies have suggested that P. freudenreichii may exert anti-inflammatory effects, modulate gut microbiota, and improve gut barrier integrity—mechanisms relevant to IBS symptom management. For example, a small randomized controlled trial (RCT) found that a probiotic mixture containing P. freudenreichii helped reduce abdominal discomfort in IBS patients, but the effect could not be attributed solely to this strain due to the multi-strain formulation. Other in vitro and animal studies indicate the species’ ability to produce short-chain fatty acids (like propionate) and B vitamins, which could confer gut health benefits. However, high-quality, large-scale clinical trials using P. freudenreichii alone in IBS populations are still lacking. Thus, while there is some scientific rationale and early clinical evidence, the overall strength of evidence is currently weak to moderate.

In summary, the use of P. freudenreichii for IBS is supported by limited scientific evidence, and more robust clinical validation is required before strong recommendations can be made.

More about Propionibacterium freudenreichii
More about Irritable Bowel Syndrome

Other ingredients used for Irritable Bowel Syndrome

2'-Fucosyllactose
Agastache
Agrimonia pilosa
Akkermansia muciniphila
Alexandrian senna
Algae
Aloe vera
alpha-galactosidase
alpha-pinene
amino acids
anise
asafoetida
atractylodes
Bacillus
bacillus clausii
bacillus coagulans
Bacillus indicus
Bacillus licheniformis
bacillus subtilis
bacteria
bayleaf
belleric myrobalan
benegut perilla (proprietary)
beta caryophyllene
betony
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bilberry
bio ecolian (proprietary)
bitter principals
black salt
blackberry
Boswellia
Boswellic Acid
bran
butyrate triglyceride
butyric acid
cannabidiol
chen pi
chia seed
chlorella
chrysanthemum
cinnamon
citron
Clerodendrum indicum
coriander
cumin
curcumin
Dichrostachys glomerata
dragonhead
Enterococcus
enzyme blend
fennel
ferula assafoetida
fiber
fig
flaxseed
Frangula
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
Fumaria parviflora
galactomannan
galactooligosaccharides
ginger
Glucooligosaccharides
green banana
green tea
guar gum
hemicellulose
holarrhena antidysenterica
hyssop
Indian coraltree
Indian frankincense
inulin
isomalto-oligosaccharide
Kluyveromyces marxianus
L-glutamine
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus helveticus
Lactobacillus johnsonii
Lactobacillus kefiranofaciens
Lactobacillus kefiri
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
Lactococcus lactis
Lactococcus rhamnosus
Leuconostoc
locust bean gum
lovage
Lysimachia
Malva sylvestris
Marshmallow
Meadowsweet
Mentha haplocalyx
Methylcellulose
Mucilage
Nardostachys
oat
Oligosaccharides
Operculina turpethum
Palmitoylethanolamide (PEA)
Pediococcus acidilactici
Pediococcus pentosaceus
Peppermint
Phellodendron
Pimpinella
Plectranthus amboinicus
plum fruit
pomegranate
Portulaca
probiotics
Propionibacterium freudenreichii
psyllium
quercetin
quince
resveratrol
rhubarb
Rhus coriaria
Rubus
Saccharomyces boulardii
Sagebrush
Salvia
Sanguisorba
Savory
senna
Slippery Elm
slippery elm bark
spearmint leaf
streptococcus thermophilus
tributyrin
turmeric
Viburnum
vitamin D
White oak
xylooligosaccharides
Yacon
Zinc
Zingerone

Other health conditions supported by Propionibacterium freudenreichii

Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Colitis
Digestion (poor)
Eczema
Inflammation
Inflammatory Bowel Disorders
Irritable Bowel Syndrome

Products containing Propionibacterium freudenreichii

We currently have no products on Vitabase that contain this ingredient.