Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Synopsis: Xylooligosaccharides (XOS) are prebiotic fibers that have gained recent scientific interest for their potential role in managing Irritable Bowel Syndrome (IBS). XOS are non-digestible carbohydrates that selectively stimulate the growth of beneficial gut bacteria, particularly Bifidobacteria and Lactobacilli. Several small-scale clinical trials and animal studies have explored their effects on gut health, with some showing that XOS supplementation can improve stool consistency, reduce bloating, and decrease abdominal discomfort in IBS patients. The proposed mechanism involves modulation of the gut microbiota, which may help restore balance in IBS patients who often present with dysbiosis (an imbalance of gut bacteria).

However, the overall evidence remains limited. Most human studies are short-term, involve small sample sizes, and often include participants with general gastrointestinal discomfort rather than strictly diagnosed IBS according to established criteria. A few randomized controlled trials have shown modest improvements in IBS symptoms with XOS supplementation compared to placebo, but the benefits are not universally observed, and more robust, large-scale studies are needed to confirm efficacy and determine optimal dosages. Current clinical guidelines do not yet specifically recommend XOS for IBS, but ongoing research may clarify its potential. Therefore, while there is scientific rationale and preliminary evidence, the strength of evidence supporting XOS for IBS is currently rated moderate to low (2/5).

More about xylooligosaccharides
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Products containing xylooligosaccharides

Vitabase 7 Day Colon Cleanse
Pure Encapsulations Poly-Prebiotic Powder
Designs For Health PrebioMed™ XOS
Vitabase Probiotic Blend
Pure Encapsulations PureLean® Fiber