Evidence supporting the use of: Allantoin
For the health condition: Itching

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allantoin is a compound commonly found in many over-the-counter topical preparations for skin protection and healing. Its use for treating itching (pruritus) is supported by some scientific evidence, though the strength of this evidence is modest. Allantoin acts primarily as a skin protectant and keratolytic agent, promoting the shedding of dead skin cells and facilitating the growth of new, healthy tissue. It is known to have moisturizing properties that help soothe and soften the skin, which can indirectly relieve itching associated with dryness, minor wounds, or irritation. Clinical studies specifically focusing on allantoin’s effectiveness for itching are limited, but its inclusion in dermatological products is often based on its ability to form a protective barrier and its mild anti-irritant effects. Regulatory agencies such as the U.S. FDA recognize allantoin as a safe and effective skin protectant for minor cuts, scrapes, and burns, which can be accompanied by itching. However, direct evidence from large-scale, controlled trials specifically evaluating allantoin for pruritus is lacking. Overall, while allantoin is commonly used and generally recognized as beneficial for skin comfort and protection, the scientific evidence supporting its use specifically for itching is moderate at best, and primarily extrapolated from its broader skin-soothing and healing properties rather than from targeted anti-itch studies.

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Products containing Allantoin

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