Evidence supporting the use of: Aloe Polysaccharide
For the health condition: Itching

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Aloe polysaccharides, found in Aloe vera gel, have been traditionally used to alleviate itching (pruritus), particularly in the context of minor burns, insect bites, and skin irritations. The use of Aloe for soothing the skin dates back centuries in various cultures, where Aloe gel was applied topically for its cooling and moisturizing properties. The mechanism is thought to involve the formation of a protective layer and hydration of the skin, which can help reduce sensations of itchiness. However, scientific evidence specifically supporting Aloe polysaccharides for itching is limited. Some in vitro and animal studies have indicated that Aloe components (including polysaccharides like acemannan) can exert anti-inflammatory effects, which might indirectly reduce itch associated with inflammation. Clinical trials on Aloe gel for itching are sparse, and those that exist often combine Aloe with other ingredients or study it in the context of conditions such as eczema or psoriasis, sometimes with mixed results. As such, the use of Aloe polysaccharides for itching is primarily justified by traditional use and anecdotal reports, rather than robust scientific validation.

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