Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bisabolol, a naturally occurring monocyclic sesquiterpene alcohol found in the essential oil of German chamomile (Matricaria recutita), is commonly used in cosmetics and topical formulations for its soothing and anti-inflammatory properties. Scientific evidence supports its role in alleviating itching (pruritus), primarily due to its anti-inflammatory activity. Several in vitro and in vivo studies have shown that bisabolol can inhibit the production of pro-inflammatory cytokines and mediators such as prostaglandins and leukotrienes, which are involved in the sensation of itch.

Topical bisabolol has demonstrated efficacy in reducing skin irritation and pruritus in clinical and preclinical settings, often in combination with other soothing agents. Its use is common in products formulated for sensitive or compromised skin, where itching and erythema are concerns. The mechanism likely involves both direct anti-inflammatory effects and an ability to soothe skin by enhancing skin barrier repair.

While robust randomized controlled trials specifically evaluating bisabolol for itching are limited, the existing preclinical and clinical data, along with its widespread use in dermatological products for sensitive and itchy skin, justify a moderate evidence rating. Overall, bisabolol's anti-inflammatory and calming effects provide scientific rationale for its use to support or treat itching.

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Other ingredients used for Itching

Other health conditions supported by bisabolol

Products containing bisabolol