Calendula (Calendula officinalis), also known as marigold, has been traditionally used for various skin ailments, including itching. In recent years, some scientific studies have explored its efficacy in dermatological conditions. Calendula contains flavonoids, triterpenoids, and other bioactive compounds thought to exert anti-inflammatory, wound-healing, and soothing effects on the skin.

Several small clinical trials and in vitro studies suggest that topical calendula preparations may reduce inflammation and irritation, which can contribute to relief from itching. For instance, a few randomized controlled trials have compared calendula ointments or creams with standard treatments for conditions like dermatitis, radiation-induced skin reactions, and diaper rash, often noting improvements in symptoms like erythema and itching. However, these studies tend to be limited by small sample sizes, variability in product formulations, and methodological weaknesses.

Systematic reviews and meta-analyses acknowledge the potential benefits of calendula but generally conclude that the quality of evidence remains low, and more robust, large-scale trials are needed. Calendula is generally considered safe for topical use, though rare allergic reactions have been reported.

In summary, there is some scientific evidence supporting the use of calendula for itching, but it is limited and not conclusive. The evidence currently rates as low to moderate in quality and strength.