Evidence supporting the use of: Cynanchum otophyllum
For the health condition: Itching

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Cynanchum otophyllum, also known as Qing Yang Dan (青羊胆) in traditional Chinese medicine (TCM), has been historically documented in herbal texts and folk medicine for various uses, primarily as an anti-inflammatory and detoxifying agent. Its use for itching (pruritus) appears to be rooted in traditional practices where it is included in formulas intended to "clear heat" and "remove toxins," concepts in TCM believed to relate to skin conditions, including those that cause itching or rashes. However, direct classical references specifically citing Cynanchum otophyllum as a primary remedy for itching are limited, and more often it is used in combination with other herbs.

From a scientific perspective, there is a lack of robust pharmacological studies directly linking Cynanchum otophyllum or its constituents to anti-itch (antipruritic) effects in humans or animals. The available literature is sparse and tends to focus on other potential effects such as anti-inflammatory or immunomodulatory actions, which might indirectly relieve symptoms associated with itching. No well-controlled clinical trials or mechanistic studies have been published to specifically validate its efficacy for pruritus.

In summary, the use of Cynanchum otophyllum for itching is primarily based on traditional application within TCM. The scientific evidence supporting this specific use is minimal, and its efficacy for itching remains largely anecdotal or theoretical within the framework of traditional practice.

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