Jojoba (Simmondsia chinensis) is commonly used in skincare for its moisturizing and soothing properties. The use of jojoba oil to support or treat itching (pruritus) is primarily based on its ability to mimic natural skin sebum, form a protective barrier, and reduce transepidermal water loss, which can be beneficial in conditions associated with dryness and irritation.

Several small-scale studies and reviews have evaluated jojoba oil’s potential for managing skin conditions associated with pruritus, such as eczema and psoriasis. For example, jojoba oil has demonstrated anti-inflammatory effects in vitro and in animal models, largely attributed to its fatty acid content and antioxidants. Clinical evidence remains limited; a few studies and case reports suggest it can reduce symptoms like dryness and itching when used topically, but these tend to be part of combination formulations with other ingredients known to soothe the skin.

The general consensus in dermatology is that jojoba oil is safe and well-tolerated, and it may provide symptomatic relief for mild itchiness, especially when related to dry or irritated skin. However, robust clinical trials specifically validating its anti-pruritic efficacy are lacking. Therefore, while there is some scientific rationale and limited early evidence to support its use, the overall quality of evidence is modest.