Pellitory (Parietaria officinalis), also known as wall pellitory, has been used in traditional herbal medicine for various ailments, including as a remedy for skin conditions such as itching. Historical texts, especially within European herbalism, cite pellitory as a soothing agent for inflammatory skin disorders, sometimes applied topically or taken as a tea to address itchiness. Traditional uses were based largely on empirical observation rather than any established pharmacological mechanism.

However, scientific research specifically evaluating pellitory for the treatment of itching is minimal to nonexistent. No robust clinical trials or laboratory studies have validated its effectiveness for pruritus (itching) in modern medical literature. Its use for this purpose remains largely anecdotal; the available evidence is based on historical accounts or traditional herbal formularies rather than controlled studies. Therefore, while pellitory's application for itching is rooted in tradition, the scientific evidence supporting its efficacy is very weak, and its safety profile for this indication is not well characterized.

In summary, pellitory's reputation for alleviating itching is based on traditional uses, and there is currently insufficient scientific evidence to support or refute its effectiveness for this condition.