Evidence supporting the use of: Sabadilla
For the health condition: Itching

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sabadilla (Schoenocaulon officinale) is a plant whose seeds have historically been used in traditional medicine, especially in homeopathy and folk remedies. Its use for treating itching (pruritus) is rooted in its long-standing application as an external anti-parasitic agent. In the past, extracts and powders derived from Sabadilla seeds were employed as topical treatments for lice and scabies, both of which are conditions associated with intense itching. The presumed mechanism of action was the plant's alkaloids—primarily veratridine and related compounds—which have neurotoxic effects on insects and parasites. This led to some transient relief of itching by addressing the underlying infestation. However, there is little to no robust scientific research or clinical trials validating the efficacy of Sabadilla specifically for itching unrelated to parasitic infections. Its use has declined significantly due to concerns about toxicity and the development of safer, more effective antipruritic and anti-parasitic treatments. In modern contexts, Sabadilla appears mostly in homeopathic preparations, which are highly diluted and lack evidence for efficacy beyond placebo. While traditional texts and old pharmacopoeias may mention Sabadilla for itching, this is based more on historical practice than on scientific validation.

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