Evidence supporting the use of: Camphor
For the health condition: Itching (rectal)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Camphor has a long history of traditional use for relieving itching and minor skin irritations, including rectal itching (pruritus ani). In various cultures, camphor-containing ointments and balms have been applied topically to soothe itch and discomfort due to its cooling and mild anesthetic effects. The U.S. FDA recognizes low concentrations of camphor (typically 0.1-3%) as a safe and effective ingredient in over-the-counter topical products for temporary relief of minor skin irritations and itching, although not specifically for rectal use. However, direct scientific evidence supporting camphor’s efficacy in treating rectal itching is limited. Most available data are extrapolated from its general use as an anti-pruritic and counterirritant for the skin. Mechanistically, camphor activates TRPV1 and TRPA1 receptors, producing a cooling sensation that temporarily masks the sensation of itch. Some rectal ointments marketed for hemorrhoid or pruritus ani relief may include camphor as a component, but clinical trials specifically investigating its efficacy in rectal itching are lacking. Safety also warrants attention: camphor can be toxic if ingested or used inappropriately, and high concentrations may cause skin irritation or burns, especially on sensitive mucosal tissues. In summary, the use of camphor for rectal itching is based on traditional practice and general anti-pruritic properties, but robust scientific validation for this specific indication is lacking.

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