Evidence supporting the use of: Artichoke
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Artichoke (Cynara scolymus) has a long history of use in traditional medicine, particularly in Europe and the Mediterranean region, as a remedy for various liver-related conditions, including jaundice in adults. Historical herbal texts and ethnobotanical records frequently cite artichoke leaves as a cholagogue (stimulating bile flow) and hepatoprotective agent. Folk practitioners have recommended artichoke extracts or infusions to support liver function, enhance bile secretion, and alleviate symptoms associated with jaundice, such as yellowing of the skin and eyes, digestive complaints, and general malaise.

Scientifically, artichoke contains compounds such as cynarin and chlorogenic acid, which have demonstrated some hepatoprotective and choleretic effects in laboratory and animal studies. These activities theoretically support the rationale for its use in liver dysfunctions, including conditions that cause jaundice. However, direct, high-quality clinical evidence specifically supporting the use of artichoke for treating or resolving jaundice in adults is limited. Most modern clinical studies focus on artichoke's effects on dyspepsia, hyperlipidemia, or general liver enzyme levels, rather than jaundice as a primary endpoint. Thus, while traditional use is robust, scientific validation for jaundice specifically is sparse, resulting in a moderate evidence rating.

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