Evidence supporting the use of: Premna
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Premna species, particularly Premna integrifolia (commonly known as "Agnimantha"), have a longstanding use in traditional Ayurvedic medicine for the treatment of liver disorders, including jaundice in adults. Classical Ayurvedic texts such as the Charaka Samhita and Sushruta Samhita mention Premna as part of polyherbal formulations intended for "kamala" (the Ayurvedic term for jaundice). Its bark, leaves, and roots are used in decoctions and powders thought to have hepatoprotective and anti-inflammatory effects. However, the traditional rationale is based on empirical experience, the doctrine of signatures, and centuries of anecdotal use rather than controlled scientific studies.

Scientific validation of Premna's efficacy in jaundice is limited. Some preliminary in vitro and animal studies suggest that extracts of Premna may have antioxidant, anti-inflammatory, and mild hepatoprotective activity, but robust clinical trials in humans are lacking. Reviews of ethnobotanical and pharmacological literature confirm its historical use for liver conditions but consistently note the absence of high-quality clinical evidence. Therefore, while Premna is traditionally used for jaundice, its use is not strongly supported by contemporary scientific research.

More about Premna
More about Jaundice (adults)

Other ingredients used for Jaundice (adults)

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green chiretta
annatto
artichoke
bamboo
barberry
myrobalan
betel
blackberry
bovine liver
rice
turmeric
dandelion
gooseberry
heartwood
honeysuckle
licorice root
lophatherum leaf
lovage
milk thistle
plum fruit
reishi mushroom
scrophularia root
silymarin
chickweed
typhonium
alpinia galangal
clerodendrum indicum
blackboard tree
fumaria parviflora
picrorhiza kurroa
rubia cordifolia
swertia
morus
sweetgums
birch
sheep's sorrel
peach
white oak
Acacia
Agrimony
Achyranthes
Abrus
Albizia
Ajuga
Aerva lanata
American Liverleaf
Asam gelugor
Alsonia scholaris
Agrimonia pilosa
Amor seco
Arani
Borotutu
Babchi
Blackthorn
Blepharis
Bayleaf
Beef liver
Barleria
Big Quaking Grass
Bael
Butternut
boldo
Banyan
black salt
Borassus Palm
Borassus aethiopum
Black root
Bergenia
Chinese Silkvine
Calotropis gigantea
Coriander
Clerodendrum phlomidis
Cyathula
Citron
Carry Me Seed
Chirata
Calamus
Carthamus
Colocynth
Clerodendrum indicum
Didymocarpus
Desmodium
Dichrostachys glomerata
Erodium cicutarium
Evodia
Embelia
Ficus religiosa
Ficus simplicissima
Goldthread
Giant Blazingstar
Gardenia jasminoides
Homalomena
Indian Nightshade
Indian Sarsparilla
Iridoid glycosides
Indian Coraltree
Ivy
Loquat
Lophira lanceolata
Lotus
Lycopodium
Leptadenia
Large-Leaved Linden
Little ironweed
Loranthus
Macaranga indica
Orchid
Osmanthus
Premna
Palmyra
Pulsatilla
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Pentatropis capensis
Polygonatum
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Products containing Premna

We currently have no products on Vitabase that contain this ingredient.