Evidence supporting the use of: Premna
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Premna species, particularly Premna integrifolia (commonly known as "Agnimantha"), have a longstanding use in traditional Ayurvedic medicine for the treatment of liver disorders, including jaundice in adults. Classical Ayurvedic texts such as the Charaka Samhita and Sushruta Samhita mention Premna as part of polyherbal formulations intended for "kamala" (the Ayurvedic term for jaundice). Its bark, leaves, and roots are used in decoctions and powders thought to have hepatoprotective and anti-inflammatory effects. However, the traditional rationale is based on empirical experience, the doctrine of signatures, and centuries of anecdotal use rather than controlled scientific studies.

Scientific validation of Premna's efficacy in jaundice is limited. Some preliminary in vitro and animal studies suggest that extracts of Premna may have antioxidant, anti-inflammatory, and mild hepatoprotective activity, but robust clinical trials in humans are lacking. Reviews of ethnobotanical and pharmacological literature confirm its historical use for liver conditions but consistently note the absence of high-quality clinical evidence. Therefore, while Premna is traditionally used for jaundice, its use is not strongly supported by contemporary scientific research.

More about Premna
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Other ingredients used for Jaundice (adults)

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Agrimonia pilosa
Agrimony
Ajuga
Albizia
Aloe vera
alpinia galangal
Alstonia scholaris
American Liverleaf
Amor seco
annatto
Arani
artichoke
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babchi
bael
bamboo
banyan
barberry
Barleria
bayleaf
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betel
big quaking grass
birch
black root
black salt
blackberry
blackboard tree
blackthorn
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Borassus aethiopum
borassus palm
borotutu
bovine liver
butternut
calamus
Calotropis gigantea
carry me seed
Carthamus
chickweed
Chinese silkvine
chirata
citron
Clerodendrum indicum
Clerodendrum indicum
Clerodendrum phlomidis
colocynth
coriander
Cyathula
dandelion
Desmodium
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Didymocarpus
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Erodium cicutarium
Evodia
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gooseberry
green chiretta
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honeysuckle
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iridoid glycosides
Ivy
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Leptadenia
licorice root
little ironweed
lophatherum leaf
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loquat
Loranthus
lotus
lovage
Lycopodium
Macaranga indica
Milk thistle
Morus
Myrobalan
orchid
Osmanthus
Palmyra
peach
Pentatropis capensis
Pepper Bark Tree
picrorhiza kurroa
Pimpinella
Plectranthus amboinicus
plum fruit
Polygonatum
Polygonum
Premna
Pulsatilla
Qin Jiao
reishi mushroom
rhubarb
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rice
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scrophularia root
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silymarin
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Products containing Premna

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