Evidence supporting the use of: Rubiaceae (unspecified)
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of plants from the Rubiaceae family to support or treat jaundice, particularly in adults, is primarily justified by traditional evidence. In various traditional medicine systems, including Ayurveda, Unani, and certain African and Asian folk practices, species within the Rubiaceae family (such as Oldenlandia corymbosa, Morinda citrifolia, and Hedyotis diffusa) have been used for liver-related conditions, including jaundice. Ethnobotanical surveys frequently report the use of decoctions or extracts from these plants to "cleanse the liver" or "purify the blood," which is often interpreted as supporting the management of jaundice. However, while there are some in vitro and animal studies indicating possible hepatoprotective effects for a few Rubiaceae species, there is a lack of robust clinical trials in humans to confirm efficacy or safety for jaundice treatment. Most of the current evidence remains anecdotal or is based on traditional formulations. Therefore, the evidence rating is relatively low, reflecting the gap between traditional use and scientific validation. Individuals considering these remedies should consult a healthcare provider, as jaundice can be a symptom of serious underlying conditions.

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