The use of Cyathula species (such as Cyathula prostrata or Cyathula officinalis) to support or treat jaundice in infants is primarily rooted in traditional medicine, particularly within certain regions of Asia and Africa. Ethnobotanical surveys and traditional medical texts report that Cyathula has been used for various hepatic and blood-related ailments, including jaundice. However, the documentation is largely anecdotal, based on local herbal practices and passed-down knowledge rather than systematic clinical research.

Scientifically, there is a significant lack of direct evidence supporting the efficacy or safety of Cyathula for treating neonatal jaundice. While some studies have explored potential hepatoprotective or antioxidant properties of Cyathula extracts in laboratory settings or animal models, these do not specifically address jaundice in infants, nor do they provide a clear clinical basis for its use in this context. No randomized controlled trials or robust pharmacological studies confirm its effectiveness or safety for infant jaundice.

In summary, the use of Cyathula for infant jaundice is justified by traditional practices rather than scientific validation, and the evidence supporting its use for this specific indication is weak.