Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lophatherum leaf, known as Lophatherum gracile or "Danzhuye" in traditional Chinese medicine (TCM), has a long history of use in East Asian herbal practices. It is commonly prescribed as part of herbal formulas to "clear heat" and "eliminate dampness," which, in TCM theory, correspond to symptoms such as fever, irritability, and jaundice. Historical texts and materia medica, such as the "Shennong Bencao Jing" and later TCM compilations, list Danzhuye as beneficial for conditions presenting with yellowing of the skin or eyes, which TCM practitioners interpret as jaundice. In the context of infants, Danzhuye is sometimes included in herbal decoctions to support the body’s natural detoxification processes.

However, modern scientific validation for Lophatherum leaf’s efficacy in treating neonatal jaundice is limited. Few clinical studies directly examine its effects in infants with jaundice. Most available literature consists of case reports or small-scale studies, often combining Danzhuye with other herbs, making it difficult to attribute efficacy to Lophatherum leaf alone. Some phytochemical research has identified flavonoids and other compounds with mild anti-inflammatory or diuretic effects, which could theoretically support liver and kidney function, but direct, rigorous evidence in the context of neonatal jaundice is lacking.

In summary, the use of Lophatherum leaf for infant jaundice is primarily rooted in traditional practice rather than robust scientific evidence. Its application should be approached with caution, especially in infants, pending further research.

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