Evidence supporting the use of: Comfrey
For the body system: Joints

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Comfrey (Symphytum officinale) has a long history of traditional use for supporting joint health and treating musculoskeletal ailments. Folk medicine across Europe and Asia has used comfrey externally as a poultice or ointment for joint pain, bruises, sprains, and bone fractures—hence its nickname "knitbone." The roots and leaves of comfrey contain allantoin, mucilage, and rosmarinic acid, which are believed to promote tissue repair and reduce inflammation. While modern research is limited, several small clinical trials and reviews have found topical comfrey preparations effective in reducing pain and improving function in conditions such as osteoarthritis, back pain, and sprains when compared to placebo or standard treatments. However, comfrey is not recommended for internal use due to the presence of hepatotoxic pyrrolizidine alkaloids, which can cause serious liver damage. The evidence for comfrey's topical use is promising but not robust, mostly based on traditional use and a handful of controlled studies. Regulatory agencies caution against oral use, and recommend topical products be used only on unbroken skin for short durations. Overall, comfrey’s reputation as a joint-supportive herb is primarily grounded in tradition, but it is supported by some promising, though limited, clinical data for external application.

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Other body systems supported by Comfrey

Gums
Joints
Skeletal System (Bones)
Skin

Products containing Comfrey

We currently have no products on Vitabase that contain this ingredient.