Evidence supporting the use of: Manganese Ascorbate
For the body system: Joints

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Manganese ascorbate is a compound that combines the essential trace mineral manganese with vitamin C (ascorbic acid). Its use in supporting joint health has some scientific basis, though the evidence is limited and not especially robust. Manganese is known to play a role in the synthesis of proteoglycans, which are important components of cartilage and synovial fluid in joints. Some clinical studies have investigated the use of manganese ascorbate, often in combination with other substances such as glucosamine and chondroitin, for the management of osteoarthritis symptoms. For example, a few randomized controlled trials have included manganese ascorbate as part of a multi-ingredient supplement and reported modest improvements in joint pain and function. However, these studies do not isolate the effects of manganese ascorbate itself, making it difficult to attribute benefits specifically to this compound. Additionally, the scientific validation for manganese ascorbate alone is weak, as most evidence supports only a theoretical role based on manganese's involvement in connective tissue metabolism, rather than direct clinical outcomes. There is no substantial traditional use of manganese ascorbate for joint health. Overall, while there is a scientific rationale for why manganese ascorbate might support joint health, especially as part of a combination therapy, the direct evidence for its effectiveness is limited, warranting a modest evidence rating.

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Other body systems supported by Manganese Ascorbate

Joints

Products containing Manganese Ascorbate

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