Evidence supporting the use of: Proprietary Blend (Fatty Acid or Fat/Oil supplement)
For the body system: Joints

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Fatty acid supplements—most notably omega-3 fatty acids such as EPA and DHA from fish oil—are widely used to support joint health, and their use is justified by a substantial body of scientific research. Multiple randomized controlled trials and meta-analyses have demonstrated that omega-3 supplementation can reduce symptoms of joint pain and stiffness, particularly in individuals with rheumatoid arthritis and, to a lesser extent, osteoarthritis. The proposed mechanism is the anti-inflammatory effect of omega-3 fatty acids, which modulate the production of inflammatory eicosanoids and cytokines involved in joint inflammation. Some studies show improvements in patient-reported pain scores, reduction in morning stiffness, and a decrease in the use of non-steroidal anti-inflammatory drugs (NSAIDs) in those supplementing with fish oil. While not a cure, omega-3 fatty acids are considered a useful adjunct for managing joint symptoms. There is less direct evidence for the efficacy of generic "proprietary blends" of fatty acids or other fats/oils unless they specify the inclusion of well-studied components (e.g., omega-3s). Nonetheless, the core scientific support for certain fatty acids, particularly from marine sources, justifies their use in joint health formulations.

More about Proprietary Blend (Fatty Acid or Fat/Oil supplement)
More about Joints

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black currant
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borage oil
boron
Indian frankincense
bovine
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broccoli
bromelain
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cabbage leaf
calamari oil
cartilage
cat's claw
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collagen
turmeric
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cuspidatum root
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DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fish oil
fish protein
flavonols
flaxseed
gamma linolenic acid (GLA)
gelatin
ginger
glucosamine
gokhru
gooseberry
gotu kola
green lipped mussel
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horsetail
hyaluronic acid
Indian tinospora
knotweed
krill oil
l-proline
mackerel
manganese
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
mustard seed
n-acetyl-glucosamine
nettle
olive
omega-3 fatty acids
omega-6 fatty acids
phellodendron amurense
phytocannabinoids
pine bark
pineapple
plantain
protein
quercetin
rehmannia glutinosa
rhizome
rose hips
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
scrophularia root
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specialized pro-resolving mediators (SPMs)
triphala
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seaweed
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sarsaparilla
red clover
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chickweed
gastrodia
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herbal blend (proprietary)
algae
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gravel root
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Bone Protein
Bee products
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Bee venom
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Products containing Proprietary Blend (Fatty Acid or Fat/Oil supplement)

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