Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Quercetin is a flavonoid commonly found in many fruits and vegetables, and it has been studied for its potential anti-inflammatory properties. The rationale for using quercetin to support joint health primarily comes from its ability to modulate inflammatory pathways, such as inhibiting the production of pro-inflammatory cytokines (e.g., TNF-α, IL-1β) and enzymes (e.g., COX-2) associated with joint inflammation and degradation. Several in vitro and animal studies have shown that quercetin can reduce markers of inflammation and oxidative stress relevant to joint diseases like osteoarthritis and rheumatoid arthritis. For example, animal models have demonstrated decreased joint swelling and cartilage destruction after quercetin supplementation.

However, human clinical data are limited. A handful of small randomized controlled trials have explored quercetin supplementation in patients with rheumatoid arthritis or other inflammatory joint conditions, showing modest improvements in symptoms such as morning stiffness and pain. These studies often use relatively high doses of quercetin and short durations, which limits generalizability. While the body of evidence is growing, it is not yet robust or sufficient for strong recommendations.

In summary, the use of quercetin for joint support is justified by preclinical scientific evidence and some early clinical trials, but more high-quality human research is needed to confirm efficacy and safety. Thus, the evidence rating is moderate.

More about quercetin
More about Joints

Other ingredients that support Joints

Other body systems supported by quercetin

Products containing quercetin

Pure Encapsulations Acerola/Flavonoid
Thorne Advanced Nutrients Multivitamin
Pure Encapsulations AI Formula
Pure Encapsulations Aller-Essentials
Pure Encapsulations Aller-Essentials
Designs For Health ArthroSoothe™ Supreme
Pure Encapsulations Athletic Nutrients
Pure Encapsulations Balanced Immune
Designs For Health BioFizz® Immune
Metagenics CardioLux® HDL
Designs For Health C+BioFizz®
Douglas Laboratories Cysto Renew ®
Pure Encapsulations Daily Immune
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Designs For Health DFH Complete Multi™
Designs For Health DFH Complete Multi™ with Copper
Designs For Health DFH Complete Multi™ with Copper & Iron
Thorne Diabenil
Designs For Health DopaBoost™
Designs For Health Electrolyte Synergy™
Pure Encapsulations Essential-C & Flavonoids
Pure Encapsulations Essential-C & Flavonoids
Designs For Health GI Revive®
Designs For Health GI Revive®
Designs For Health H-S-N Radiance™
Pure Encapsulations Hist Reset
Designs For Health HistaEze™
Metagenics Immune Active
Metagenics Immune Defense Pack
Designs For Health Inflammatone™
Designs For Health Inflammatone™
Designs For Health Inflammatone™
Vitabase Life's Essentials Plus
Metagenics Multigenics®
Metagenics Multigenics Chewable Orange
Metagenics Multigenics Intensive Care
Metagenics Multigenics Intensive Care without Iron
Metagenics Multigenics without Iron
Pure Encapsulations NeuroMood Pure Pack
Pure Encapsulations NeuroPure
Designs For Health OcuForce™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™ Detox Program
Designs For Health PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health PhytoBiome™
Metagenics PhytoGanix® Tropical Fruit
Designs For Health Plant Protein Cleanse
Designs For Health Plant Protein Cleanse Plus™ 570g
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations Polyphenol Nutrients
Thorne PolyResveratrol-SR
Designs For Health Primal Multi™
Vitabase Prostate Complex (Formerly Prostate Complete)
Pure Encapsulations PureDefense
Pure Encapsulations PureDefense with NAC
Pure Encapsulations PureDefense with NAC
Pure Encapsulations PureLean® Protein
Pure Encapsulations Quercetin
Pure Encapsulations Quercetin
Metagenics Quercetin 500
Vitabase Quercetin Plus
Designs For Health Quercetin-Ascorbate
Douglas Laboratories Quercetin-Bromelain Complex
Thorne Quercetin Complex Quercenase
Designs For Health Quercetin + Nettles
Thorne Quercetin Phytosome
Pure Encapsulations Quercetin UltraSorb
Thorne ResveraCel
Designs For Health Resveratrol Supreme
Designs For Health Senolytic Synergy
Metagenics Sinuplex®
Designs For Health Stellar C™
Vitabase Super Antioxidant Formula
Pure Encapsulations Th2 Modulator
Designs For Health Ultimate Antiox Full Spectrum
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive ®-EZ Swallow
Douglas Laboratories Ultra Preventive® X
Douglas Laboratories Ultra Protein Green
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Pure Encapsulations Uric Acid Formula
Designs For Health Vessel Forte™
Vitabase Vision Support
Integrative Therapeutics Vitamin C with Quercetin