Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Sulfate, most commonly in the form of glucosamine sulfate or chondroitin sulfate, is frequently used in dietary supplements aimed at supporting joint health, particularly for conditions like osteoarthritis. The rationale behind its use is based on the role sulfate groups play in the structure and function of cartilage. Chondroitin sulfate is a major component of cartilage and provides much of its resistance to compression. Glucosamine sulfate is believed to contribute to the synthesis of glycosaminoglycans, which are key molecules in cartilage maintenance.

There is a moderate body of scientific evidence supporting the use of sulfate-containing compounds (especially chondroitin sulfate and glucosamine sulfate) for joint health. Several randomized controlled trials and meta-analyses have suggested that these supplements may provide modest pain relief and improved joint function in people with osteoarthritis, especially of the knee. However, results are mixed, and some large, well-conducted studies have found little to no benefit over placebo. The effect size, when present, is generally small.

It’s important to note that "sulfate (unspecified)" is not typically used as a standalone supplement for joint support; rather, its relevance comes from its presence as a component of specific molecules like glucosamine sulfate and chondroitin sulfate. Therefore, the scientific support applies primarily to these compounds, not to sulfate ions in general.

More about Sulfate (unspecified)
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Other body systems supported by Sulfate (unspecified)

Joints

Products containing Sulfate (unspecified)

We currently have no products on Vitabase that contain this ingredient.