Evidence supporting the use of: Vitamin C (ascorbic acid)
For the body system: Joints
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin C (ascorbic acid) is scientifically recognized for its essential role in collagen synthesis, a protein crucial for the structure and function of cartilage, tendons, and ligaments within the joints. Collagen provides strength and elasticity to connective tissues, making vitamin C necessary for normal joint health and maintenance. Scientific studies show that vitamin C deficiency can lead to impaired collagen formation, resulting in joint pain and even scurvy, a disease marked by weakened connective tissue. However, while vitamin C is necessary for basic joint function and maintenance, clinical evidence supporting its use as a therapeutic supplement specifically for preventing or treating joint disorders such as osteoarthritis or rheumatoid arthritis is limited and inconclusive.
Some observational and animal studies suggest that adequate vitamin C intake may be associated with a reduced risk of developing certain joint diseases or may slow progression, likely due to its antioxidant properties and role in inflammation modulation. However, randomized controlled trials in humans have not consistently demonstrated significant improvements in joint pain, cartilage repair, or arthritis outcomes with vitamin C supplementation beyond what is required for normal nutrition. Therefore, while vitamin C is scientifically validated as necessary for joint health via its role in collagen synthesis, high-dose supplementation for joint disorders is not robustly supported by current research.
Other ingredients that support Joints
alfalfaalgal oil
amino acids
berry flavor
beta caryophyllene
black cumin
black currant
sesame
borage oil
boron
Indian frankincense
bovine
bovine gelatin
broccoli
bromelain
burdock
cabbage leaf
calamari oil
cartilage
cat's claw
cherry
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
turmeric
curcumin
cuspidatum root
devil's claw
dog rose
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fish oil
fish protein
flavonols
flaxseed
gamma linolenic acid (GLA)
gelatin
ginger
glucosamine
gokhru
gooseberry
gotu kola
green lipped mussel
guggul
horsetail
hyaluronic acid
Indian tinospora
knotweed
krill oil
l-proline
mackerel
manganese
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
mustard seed
n-acetyl-glucosamine
nettle
olive
omega-3 fatty acids
omega-6 fatty acids
phellodendron amurense
phytocannabinoids
pine bark
pineapple
plantain
protein
quercetin
rehmannia glutinosa
rhizome
rose hips
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
scrophularia root
serratiopeptidase
silicon
black ginger
specialized pro-resolving mediators (SPMs)
triphala
vitamin C
vitamin D
seaweed
water
white willow
wild yam
sarsaparilla
red clover
boneset
chickweed
gastrodia
capsicum
clerodendrum indicum
hedychium spicatum
punarnava
commiphora
paederia foetida
smilax
tinospora cordifolia
rubia cordifolia
chaff flower
peony
lingusticum wallichii
prickly ash
myrrh
juniper berries
solomon's seal
siler root
flowering quince
dioscorea
teasel
eucommia
ganoderma
morinda
zanthoxylum
birch
queen of the meadow
polyphenols
anemarrhena asphodeloides
yucca
barrenwort
wintergreen
camphor oil
coix
gentiana macrophylla
noni
herbal blend (proprietary)
algae
cayenne pepper
ashitaba
gravel root
bladderwrack
arnica
clematis
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Aralia
Animal Tissue
Antler
Avian Cartilage
Achyranthes
Anamu
Avocado
Asteracea
Acetylsalicylic acid
Abuta
Amor seco
Animal protein
Bone
Black Seed
Baikal Skullcap
Bryonia
Biopeptide
Babchi
Bidens pilosa
Balsam
Bishop's Weed
Boswellic Acid
Bayleaf
Butea monosperma
Black galingale
Barleria
Bugbane
Baicalein
Bovine Protein
berry
Bogbean
Black Gram
Boswellia
Black Poplar
Black willow
Ba Ji Tian
Bone Protein
Bee products
Bombax
Borage
bovine cartilage / glycosaminoglycan
Baicalin
Bassia scoparia
Bee venom
Bergenia
Boerhavia diffusa
Curculigo orchicides
Comfrey
Centella triterpenes
Chinese Silkvine
Caryophyllene
Cinnamomum
Chinese Mountain Ant
Crustaceans
Cod Liver Oil
Coriander
Clerodendrum phlomidis
Cinquefoil
Cyathula
Curcuminoid
Capsaicin
Chuchuhuasi
Curcumen
Cymbopogon Martini
Centella asiatica
Cetylated Fatty Acids
Cissus sicyoides
Chicken
Curcuma
Calanus finmarchicus
Campsiandra angustifolia
Cowslip
Cannabidiol
Chebulinic acid
Carthamus
Copaiba Oil
Currant
Deer Root
Deer Velvet
Drynaria
Devil's Club
Dwarf Nettle
Dimethyl sulfoxide (DMSO)
Dipsacus
Elephant Vine
Egg
Elk antler
Emu Oil
Eicosapentaenoic Acid
Evening Primrose Oil
European-Five Finger Grass
Escin
Eucommia ulmoides
Ecklonia
Flavonoids
Glycine
Glycosaminoglycans
Little ironweed
Other body systems supported by Vitamin C (ascorbic acid)
Adrenal GlandsArteries
Blood
Brain
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Intestinal System
Joints
Liver
Lungs
Mucus Membranes
Skin
Teeth