Evidence supporting the use of: Vitamin C (not specified)
For the body system: Joints

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C (ascorbic acid) is scientifically recognized for its role in supporting joint health, primarily through its involvement in collagen synthesis. Collagen is a major structural protein in cartilage, tendons, and ligaments, which are essential components of the joints. Adequate vitamin C is necessary for the enzymatic hydroxylation of proline and lysine, amino acids required for stable collagen fibers. Deficiency in vitamin C can result in weakened connective tissue, as seen in scurvy, which manifests with joint pain and poor wound healing. Additionally, vitamin C’s antioxidant properties may help reduce oxidative stress and inflammation, which are implicated in the pathogenesis of osteoarthritis and other joint disorders.

However, while epidemiological and animal studies suggest a protective effect of vitamin C on joint tissues and some observational studies have linked higher vitamin C intake with reduced risk of cartilage loss, randomized controlled trials in humans have produced mixed results. Some studies show modest benefits in slowing progression of osteoarthritis or reducing joint pain, while others do not demonstrate significant effects. Overall, the scientific evidence supports a role for vitamin C in maintaining normal joint structure and function via its biochemical roles, but there is limited clinical evidence for its efficacy as a therapeutic intervention in joint diseases.

More about Vitamin C (not specified)
More about Joints

Other ingredients that support Joints

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algal oil
amino acids
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beta caryophyllene
black cumin
black currant
sesame
borage oil
boron
Indian frankincense
bovine
bovine gelatin
broccoli
bromelain
burdock
cabbage leaf
calamari oil
cartilage
cat's claw
cherry
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
turmeric
curcumin
cuspidatum root
devil's claw
dog rose
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fish oil
fish protein
flavonols
flaxseed
gamma linolenic acid (GLA)
gelatin
ginger
glucosamine
gokhru
gooseberry
gotu kola
green lipped mussel
guggul
horsetail
hyaluronic acid
Indian tinospora
knotweed
krill oil
l-proline
mackerel
manganese
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
mustard seed
n-acetyl-glucosamine
nettle
olive
omega-3 fatty acids
omega-6 fatty acids
phellodendron amurense
phytocannabinoids
pine bark
pineapple
plantain
protein
quercetin
rehmannia glutinosa
rhizome
rose hips
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
scrophularia root
serratiopeptidase
silicon
black ginger
specialized pro-resolving mediators (SPMs)
triphala
vitamin C
vitamin D
seaweed
water
white willow
wild yam
sarsaparilla
red clover
boneset
chickweed
gastrodia
capsicum
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hedychium spicatum
punarnava
commiphora
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camphor oil
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gentiana macrophylla
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herbal blend (proprietary)
algae
cayenne pepper
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gravel root
bladderwrack
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clematis
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
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Animal Tissue
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Boswellic Acid
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Bugbane
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Bogbean
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Boswellia
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Bone Protein
Bee products
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bovine cartilage / glycosaminoglycan
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Bee venom
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Elk antler
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Products containing Vitamin C (not specified)

We currently have no products on Vitabase that contain this ingredient.