Evidence supporting the use of: Cleavers
For the health condition: Kidney Stones

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Cleavers (Galium aparine) has a long history of use in traditional herbal medicine, particularly in Europe and North America, for supporting urinary tract health and as a remedy for kidney and bladder conditions, including kidney stones. Traditional herbalists have used cleavers as a diuretic and "depurative" (blood cleanser), believing it helps flush out the urinary system and may assist in expelling small stones or gravel from the kidneys and bladder. The plant’s purported action is attributed to its high water content, mild diuretic effect, and possible ability to soothe mucous membranes. However, scientific validation for these uses is limited. There are few clinical studies specifically examining cleavers for kidney stones. Most evidence consists of in vitro studies or animal research suggesting mild anti-inflammatory, diuretic, and antioxidant properties. These findings are promising but not definitive in the context of kidney stone prevention or treatment. Major herbal reference texts and monographs (e.g., European Medicines Agency, Commission E) recognize cleavers for traditional use in urinary complaints but do not list robust clinical evidence for kidney stones. In summary, cleavers is primarily used based on traditional knowledge rather than scientific validation. While it may offer mild diuretic support, anyone with kidney stones should consult a healthcare provider for evidence-based treatment, as cleavers is not a substitute for conventional therapies.

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