Evidence supporting the use of: Madder (unspecified)
For the health condition: Kidney Stones

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Madder (commonly referring to Rubia cordifolia or Rubia tinctorum) has a long history of use in traditional systems of medicine, particularly Ayurveda and Traditional Chinese Medicine, for the treatment of kidney stones. Traditionally, Madder root has been used as a diuretic and lithotriptic (stone-dissolving) agent. It is believed to help break down and eliminate calculi (stones) from the urinary tract, although these claims are largely rooted in empirical herbal practices rather than robust scientific evidence.

Scientific studies on Madder's efficacy for kidney stones are limited and mostly preclinical. Some in vitro and animal studies suggest that extracts of Madder may have an effect on the crystallization process of calcium oxalate, the main component of most kidney stones. For instance, certain compounds isolated from Madder, such as ruberythric acid, have shown potential inhibition of stone formation in animal models. However, these findings have not been conclusively demonstrated in human clinical trials, and concerns exist regarding the safety and toxicity of Madder, particularly its potential carcinogenicity and nephrotoxicity (kidney toxicity) with prolonged use.

In summary, the use of Madder for kidney stones is primarily supported by traditional use, with only limited and preliminary scientific evidence. Its use is not widely endorsed in modern clinical practice due to insufficient high-quality data and safety concerns.

More about Madder (unspecified)
More about Kidney Stones

Other health conditions supported by Madder (unspecified)

Arthritis
Edema
Inflammation
Kidney Stones
Liver Detoxification
Rheumatoid Arthritis
Ulcers

Products containing Madder (unspecified)

We currently have no products on Vitabase that contain this ingredient.