Evidence supporting the use of: Agrimonia pilosa
For the body system: Kidneys

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Agrimonia pilosa, known as hairy agrimony, has a long history of use in traditional Chinese medicine (TCM) and other East Asian medical systems. Traditionally, it is used to support the kidneys, as well as to address conditions such as kidney weakness, urinary disorders, and bleeding (e.g., hematuria). In TCM, Agrimonia pilosa is thought to "tonify" the kidneys, stop bleeding, and treat diarrhea. However, the rationale is based on TCM theory, which correlates organ systems with broader physiological functions rather than strictly anatomical kidneys. Historically, formulas including Agrimonia pilosa are documented in classical medical texts for urinary and kidney-related conditions. Modern scientific studies on Agrimonia pilosa primarily focus on its anti-inflammatory, antioxidant, and hemostatic properties. Some in vitro and animal studies have noted protective effects against kidney damage, such as reducing markers of nephrotoxicity or ameliorating oxidative stress in renal tissues. However, these studies are limited in scope, and robust clinical trials in humans are lacking. As such, while traditional use is well documented, scientific evidence supporting its efficacy for kidney health remains preliminary and insufficient for strong validation. Therefore, the use of Agrimonia pilosa to support the kidneys is justified mainly by tradition, with some early but inconclusive scientific interest.

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