Eastern Red Cedar (Juniperus virginiana) has a long history of traditional use in Native American and folk herbal medicine, often as a remedy for urinary tract issues and to support kidney function. The berries and leaves have been used in teas or infusions thought to act as diuretics, which theoretically could support the kidneys by increasing urine output and flushing the urinary tract. However, these uses are based primarily on historical and ethnobotanical records rather than clinical research.

Scientifically, there is very limited evidence supporting the efficacy or safety of Eastern Red Cedar for kidney support. Most studies focus on its antimicrobial, antifungal, and insect-repellent properties, rather than renal effects. There are also concerns about toxicity, particularly with the essential oils and in high doses, which can be harmful to the kidneys and other organs. As such, while its use for the kidneys is grounded in tradition, it is not substantiated by modern clinical data, and caution is advised regarding its internal use.