Evidence supporting the use of: Polyphenols (unspecified)
For the body system: Kidneys

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Polyphenols, a diverse group of naturally occurring compounds found in plants, have been studied for their antioxidant, anti-inflammatory, and protective effects on various body systems, including the kidneys. Scientific studies, primarily in vitro and in animal models, suggest that polyphenols—especially those found in foods like green tea, berries, and grapes—can help attenuate oxidative stress and inflammation in renal tissues. These mechanisms may theoretically protect against kidney damage and support overall renal function, particularly in the context of chronic kidney disease (CKD) or exposure to nephrotoxic agents.

However, direct human clinical evidence linking polyphenol supplementation (unspecified source) to improved kidney function or disease prevention is limited and inconsistent. Most human trials focus on specific polyphenols (such as resveratrol or catechins) rather than the broad category. Some observational data do suggest that diets rich in polyphenol-containing foods are associated with lower risk of CKD, but causality cannot be established. There is also a lack of consensus on effective dosages or best sources for renal support.

In summary, while there is a plausible scientific rationale and some preclinical evidence supporting the idea that polyphenols may benefit kidney health, robust clinical data in humans are lacking. Therefore, the evidence is rated as modest (2/5), and polyphenols should not be considered a primary or sole intervention for kidney support without further research.

More about Polyphenols (unspecified)
More about Kidneys

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Products containing Polyphenols (unspecified)

We currently have no products on Vitabase that contain this ingredient.