Evidence supporting the use of: Stephania root
For the body system: Kidneys

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Stephania root, particularly from the species Stephania tetrandra (known as Han Fang Ji in Traditional Chinese Medicine), has a long history of use in traditional herbal practices. In Chinese herbalism, it is valued for dispelling "wind-dampness," promoting urination, and reducing swelling. These properties are interpreted in TCM as supporting the kidney and urinary systems, especially in cases of edema or joint pain. However, while its traditional use for supporting the kidneys is well-documented in historical texts and herbal formularies, there is limited modern scientific research directly validating these effects. Most available studies focus on its anti-inflammatory and diuretic properties, and there is a lack of large-scale, high-quality clinical trials that confirm its efficacy or safety specifically for kidney health in humans. Moreover, some related species in the Stephania genus may contain toxic alkaloids, and confusion with Aristolochia species (which contain nephrotoxic aristolochic acid) has led to documented cases of kidney damage. Therefore, while traditional use supports its association with the kidney body system, scientific evidence remains sparse and caution is warranted when considering its use.

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Products containing Stephania root

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