Evidence supporting the use of: Thymoquinone
For the body system: Kidneys

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Thymoquinone is a bioactive compound found in the seeds of Nigella sativa (black cumin). Its use to support kidney health is primarily rooted in traditional medicine, especially in Middle Eastern and South Asian cultures, where black seed has been used for centuries to promote general well-being and address various ailments, including those related to the kidneys. Some traditional remedies involve using Nigella sativa to alleviate symptoms of kidney stones, inflammation, and nephrotoxicity.

Modern research on thymoquinone's effects on the kidney is limited and largely preclinical. Animal studies suggest possible nephroprotective effects, mostly attributed to thymoquinone’s antioxidant and anti-inflammatory properties. For example, some rodent studies have shown protective effects against chemically-induced kidney damage and improved kidney function markers. However, these findings have not yet been robustly confirmed in human clinical trials, and the dosages and preparations used in traditional contexts differ from those in experimental settings.

Overall, while traditional use of thymoquinone and black seed for kidney support is well documented, scientific evidence in humans is lacking. As such, any recommendation for its use should be approached with caution, and more high-quality clinical research is needed to confirm efficacy and safety in supporting kidney health.

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Products containing Thymoquinone

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