Evidence supporting the use of: Hydrolyzed gelatin
For the health condition: Knees (weak)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Hydrolyzed gelatin, often marketed as collagen hydrolysate, has been studied for its potential benefits in supporting joint health, including the knees. The rationale is that gelatin is rich in amino acids like glycine and proline, which are essential components of collagen, a structural protein in cartilage and connective tissue. Several small clinical studies and reviews have investigated whether oral supplementation with hydrolyzed gelatin or collagen can reduce joint pain or improve joint function, particularly in populations with osteoarthritis or exercise-induced joint discomfort.
While some studies have shown modest improvements in joint pain and function compared to placebo, the overall quality of evidence is low to moderate. A few randomized controlled trials report statistically significant reductions in joint pain among athletes or older adults taking collagen supplements, but the clinical significance is debated. Mechanistically, limited data suggest that hydrolyzed gelatin may increase collagen synthesis in cartilage.
Major medical organizations, such as the American College of Rheumatology, do not currently recommend gelatin or collagen supplements for osteoarthritis due to insufficient high-quality evidence. Most systematic reviews conclude that more rigorous, large-scale research is needed to confirm benefits. In summary, there is some scientific evidence supporting the use of hydrolyzed gelatin for knee/joint support, but it is limited in strength and consistency.
Other health conditions supported by Hydrolyzed gelatin
ArthritisCartilage Damage
Inflammation
Injuries
Knees (weak)
Ligaments (torn or injured)
Wounds and Sores